Journal Articles
Published Research
The following is a summary of journal publications by Associate Professor Knowles. Click on the references below for further details.
Journal Articles
2012
blank
Gondalia, S., Palombo, E., Knowles, S., Cox, S. B., Meyer, D., & Austin, D. (2012). Molecular characterization of gastrointestinal microbiota in children with autism (with and without gastrointestinal dysfunction) and their neurotypical siblings. Autism Research, 5(6) (Dec 2012), pp. 419-427.
Many children with autism spectrum disorders (ASDs) suffer from gastrointestinal problems such as diarrhoea, constipation and abdominal pain. This has stimulated investigations into possible abnormalities of intestinal microbiota in autistic patients. Therefore, we designed this study to identify differences (and/or similarities) in the microbiota of children with autism (without gastrointestinal dysfunction: n = 23; with gastrointestinal dysfunction: n = 28) and their neurotypical siblings (n = 53) who share a similar environment using bacterial tag-encoded FLX amplicon pyrosequencing. Regardless of the diagnosis and sociodemographic characteristics, overall, Firmicutes (70%), Bacteroidetes (20%) and Proteobacteria (4%) were the most dominant phyla in samples. Results did not indicate clinically meaningful differences between groups. The data do not support the hypothesis that the gastrointestinal microbiota of children with ASD plays a role in the symptomatology of ASD. Other explanations for the gastrointestinal dysfunction in this population should be considered including elevated anxiety and self-restricted diets.
URL: http://onlinelibrary.wiley.com/doi/10.1002/aur.1253/full
Knowles, S. R., Hyde, M. K., & White, K. M. (2012). Predictors of young people's charitable intentions to donate money: An extended theory of planned behaviour perspective. Journal of Applied Social Psychology, 42(9), 2096-2110. doi: 10.1111/j.1559-1816.2012.00932.x
An extended theory of planned behavior (TPB) was used to predict young people’s intentions to donate money to charities in the future. Students (N = 210; 18–24 years) completed a questionnaire assessing their attitude, subjective norm, perceived behavioral control (PBC), moral obligation, past behavior, and intentions toward donating money. Regression analyses revealed that the extended TPB explained 61% of the variance in intentions to donate money. Attitude, PBC, moral norm, and past behavior predicted intentions, representing future targets for charitable-giving interventions.
URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1559-1816.2012.00932.x/full